3KGF
The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis complexed with phenylalanine and tryptophan
3KGF の概要
エントリーDOI | 10.2210/pdb3kgf/pdb |
関連するPDBエントリー | 2B7O |
分子名称 | Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG, PHENYLALANINE, TRYPTOPHAN, ... (9 entities in total) |
機能のキーワード | mycobacterium tuberculosis, dah7p synthase, shikimate pathway, aromatic biosynthesis, evolutionary relationships, transferase, phe+trp-bound, augmented tim-barrel structure, structural genomics, mycobacterium tuberculosis structural proteomics project, xmtb |
由来する生物種 | Mycobacterium tuberculosis |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 104692.13 |
構造登録者 | Parker, E.J.,Jameson, G.B.,Jiao, W.,Webby, C.J.,Baker, E.N.,Baker, H.M.,Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) (登録日: 2009-10-29, 公開日: 2010-07-28, 最終更新日: 2023-11-01) |
主引用文献 | Webby, C.J.,Jiao, W.,Hutton, R.D.,Blackmore, N.J.,Baker, H.M.,Baker, E.N.,Jameson, G.B.,Parker, E.J. Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis J.Biol.Chem., 285:30567-30576, 2010 Cited by PubMed: 20667835DOI: 10.1074/jbc.M110.111856 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2 Å) |
構造検証レポート
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