3K0V

Removal of sugars and sugars-like molecules from the solution by C-lobe of lactoferrin: Crystal structure of the complex of C-lobe with beta-D-glucopyranosyl-(1->4)-beta-D-galactopyranosyl-(1->4)-alpha-D-glucopyranose at 1.9 A resolution

Summary for 3K0V

• Entry DOI: 10.2210/pdb3k0v/pdb
• Related: 2DWA 2DXY 3IBO
• Descriptor: Lactotransferrin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• Functional Keywords: complex, dextrin, c-lobe, antibiotic, antimicrobial, disulfide bond, glycoprotein, hydrolase, ion transport, iron, iron transport, metal-binding, phosphoprotein, protease, secreted, serine protease, transport
• Biological source: Bos taurus (bovine,cow,domestic cattle,domestic cow)
• Total number of polymer chains: 1
• Total formula weight: 40100.16

Authors

Mir, R.,Vikram, G.,Sinha, M.,Singh, N.,Sharma, S.,Kaur, P.,Singh, T.P. (deposition date: 2009-09-25, release date: 2009-10-13, Last modification date: 2023-09-06)

• Primary citation: Mir, R.,Kumar, R.P.,Singh, N.,Vikram, G.P.,Sinha, M.,Bhushan, A.,Kaur, P.,Srinivasan, A.,Sharma, S.,Singh, T.P.; Specific interactions of C-terminal half (C-lobe) of lactoferrin protein with edible sugars: binding and structural studies with implications on diabetes.; Int.J.Biol.Macromol., 47:50-59, 2010; PubMed: 20371371; DOI: 10.1016/j.ijbiomac.2010.03.021

Experimental method

X-RAY DIFFRACTION (1.91 Å)