3K0V

Removal of sugars and sugars-like molecules from the solution by C-lobe of lactoferrin: Crystal structure of the complex of C-lobe with beta-D-glucopyranosyl-(1->4)-beta-D-galactopyranosyl-(1->4)-alpha-D-glucopyranose at 1.9 A resolution

3K0V の概要

• エントリーDOI: 10.2210/pdb3k0v/pdb
• 関連するPDBエントリー: 2DWA 2DXY 3IBO
• 分子名称: Lactotransferrin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: complex, dextrin, c-lobe, antibiotic, antimicrobial, disulfide bond, glycoprotein, hydrolase, ion transport, iron, iron transport, metal-binding, phosphoprotein, protease, secreted, serine protease, transport
• 由来する生物種: Bos taurus (bovine,cow,domestic cattle,domestic cow)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 40100.16

構造登録者

Mir, R.,Vikram, G.,Sinha, M.,Singh, N.,Sharma, S.,Kaur, P.,Singh, T.P. (登録日: 2009-09-25, 公開日: 2009-10-13, 最終更新日: 2023-09-06)

• 主引用文献: Mir, R.,Kumar, R.P.,Singh, N.,Vikram, G.P.,Sinha, M.,Bhushan, A.,Kaur, P.,Srinivasan, A.,Sharma, S.,Singh, T.P.; Specific interactions of C-terminal half (C-lobe) of lactoferrin protein with edible sugars: binding and structural studies with implications on diabetes.; Int.J.Biol.Macromol., 47:50-59, 2010; PubMed: 20371371; DOI: 10.1016/j.ijbiomac.2010.03.021

実験手法

X-RAY DIFFRACTION (1.91 Å)