3JVR
Characterization of the Chk1 allosteric inhibitor binding site
Summary for 3JVR
Entry DOI | 10.2210/pdb3jvr/pdb |
Related | 3JVS |
Descriptor | Serine/threonine-protein kinase Chk1, (1S)-1-(1H-benzimidazol-2-yl)ethyl (3,4-dichlorophenyl)carbamate (3 entities in total) |
Functional Keywords | protein kinase, atp-binding, cell cycle, cytoplasm, dna damage, dna repair, isopeptide bond, kinase, nucleotide-binding, nucleus, phosphoprotein, polymorphism, serine/threonine-protein kinase, transferase, ubl conjugation |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: O14757 |
Total number of polymer chains | 1 |
Total formula weight | 31605.17 |
Authors | Chen, P. (deposition date: 2009-09-17, release date: 2009-10-06, Last modification date: 2024-02-21) |
Primary citation | Vanderpool, D.,Johnson, T.O.,Ping, C.,Bergqvist, S.,Alton, G.,Phonephaly, S.,Rui, E.,Luo, C.,Deng, Y.L.,Grant, S.,Quenzer, T.,Margosiak, S.,Register, J.,Brown, E.,Ermolieff, J. Characterization of the CHK1 allosteric inhibitor binding site. Biochemistry, 48:9823-9830, 2009 Cited by PubMed: 19743875DOI: 10.1021/bi900258v PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.76 Å) |
Structure validation
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