3JTI

Crystal structure of the complex formed between Phospholipase A2 with beta-amyloid fragment, Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met at 1.8 A resolution

Summary for 3JTI

• Entry DOI: 10.2210/pdb3jti/pdb
• Related: 3GCI
• Descriptor: Phospholipase A2 isoform 3, octapeptide from Amyloid beta A4 protein, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: phospholipase a2, heptapeptide, amyloid beta, hydrolase, lipid degradation, disulfide bond, metal-binding, secreted, amyloid, amyloidosis, protease inhibitor, proteoglycan, serine protease inhibitor
• Biological source: Naja sagittifera (Andaman cobra); More
• Cellular location: Secreted: P60045; Membrane; Single-pass type I membrane protein: P05067
• Total number of polymer chains: 2
• Total formula weight: 13971.64

Authors

Pandey, N.,Mirza, Z.,Vikram, G.,Singh, N.,Bhushan, A.,Kaur, P.,Srinivasan, A.,Sharma, S.,Singh, T.P. (deposition date: 2009-09-12, release date: 2010-07-21, Last modification date: 2023-11-01)

• Primary citation: Pandey, N.,Mirza, Z.,Vikram, G.,Singh, N.,Bhushan, A.,Kaur, P.,Srinivasan, A.,Sharma, S.,Singh, T.P.; Crystal structure of the complex formed between Phospholipase A2 with beta-amyloid fragment, Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met at 1.8 A resolution; To be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)