3JS3

Crystal structure of type I 3-dehydroquinate dehydratase (aroD) from Clostridium difficile with covalent reaction intermediate

3JS3 の概要

• エントリーDOI: 10.2210/pdb3js3/pdb
• 分子名称: 3-dehydroquinate dehydratase, 3-AMINO-4,5-DIHYDROXY-CYCLOHEX-1-ENECARBOXYLATE (3 entities in total)
• 機能のキーワード: type i 3-dehydroquinate dehydratase, arod, covalent reaction intermediate, amino-acid biosynthesis, aromatic amino acid biosynthesis, lyase, schiff base, structural genomics, center for structural genomics of infectious diseases, csgid
• 由来する生物種: Clostridium difficile
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 117440.86

構造登録者

Minasov, G.,Light, S.H.,Shuvalova, L.,Dubrovska, I.,Winsor, J.,Peterson, S.N.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2009-09-09, 公開日: 2009-09-22, 最終更新日: 2023-09-06)

• 主引用文献: Light, S.H.,Minasov, G.,Shuvalova, L.,Duban, M.E.,Caffrey, M.,Anderson, W.F.,Lavie, A.; Insights into the mechanism of type I dehydroquinate dehydratases from structures of reaction intermediates.; J.Biol.Chem., 286:3531-3539, 2011; PubMed: 21087925; DOI: 10.1074/jbc.M110.192831

実験手法