3JAU

The cryoEM map of EV71 mature viron in complex with the Fab fragment of antibody D5

3JAU の概要

• エントリーDOI: 10.2210/pdb3jau/pdb
• EMDBエントリー: 6366
• 分子名称: Capsid protein VP1, Heavy chain of Fab fragment variable region of antibody D5, Light chain of Fab fragment variable region of antibody D5 (3 entities in total)
• 機能のキーワード: enterovirus 71(ev71), virus-antibody complex, bivalent binding, high resolution cryo-em, virus-immune system complex, virus/immune system
• 由来する生物種: Human enterovirus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 27139.91

構造登録者

Fan, C.,Ye, X.H.,Ku, Z.Q.,Zuo, T.,Kong, L.L.,Zhang, C.,Shi, J.P.,Liu, Q.W.,Chen, T.,Zhang, Y.Y.,Jiang, W.,Zhang, L.Q.,Huang, Z.,Cong, Y. (登録日: 2015-06-24, 公開日: 2016-02-10, 最終更新日: 2019-12-18)

• 主引用文献: Ye, X.H.,Fan, C.,Ku, Z.Q.,Zuo, T.,Kong, L.L.,Zhang, C.,Shi, J.P.,Liu, Q.W.,Chen, T.,Zhang, Y.Y.,Jiang, W.,Zhang, L.Q.,Huang, Z.,Cong, Y.; Structural Basis for Recognition of Human Enterovirus 71 by a Bivalent Broadly Neutralizing Monoclonal Antibody; Plos Pathog., 12:e1005454-e1005454, 2016; PubMed: 26938634; DOI: 10.1371/journal.ppat.1005454

実験手法

ELECTRON MICROSCOPY (4.8 Å)