3J70
Model of gp120, including variable regions, in complex with CD4 and 17b
Summary for 3J70
Entry DOI | 10.2210/pdb3j70/pdb |
EMDB information | 5020 |
Descriptor | monoclonal antibody 17b light chain, monoclonal antibody 17b heavy chain, T-cell surface glycoprotein CD4, ... (5 entities in total) |
Functional Keywords | gp120, v1v2, cd4, 17b, viral protein-immune system complex, viral protein/immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P01730 Cell membrane ; Single-pass type I membrane protein : P04578 |
Total number of polymer chains | 15 |
Total formula weight | 391383.66 |
Authors | |
Primary citation | Rasheed, M.,Bettadapura, R.,Bajaj, C. Computational Refinement and Validation Protocol for Proteins with Large Variable Regions Applied to Model HIV Env Spike in CD4 and 17b Bound State. Structure, 23:1138-1149, 2015 Cited by PubMed: 26039348DOI: 10.1016/j.str.2015.03.026 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (20 Å) |
Structure validation
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