3J63
Unified assembly mechanism of ASC-dependent inflammasomes
Summary for 3J63
Entry DOI | 10.2210/pdb3j63/pdb |
EMDB information | 5830 |
Descriptor | Apoptosis-associated speck-like protein containing a CARD (1 entity in total) |
Functional Keywords | helical polymer, variable twist, death domain, apoptosis |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 15 |
Total formula weight | 151374.98 |
Authors | Lu, A.,Magupalli, V.G.,Ruan, J.,Yin, Q.,Atianand, M.K.,Vos, M.,Schroder, G.F.,Fitzgerald, K.A.,Wu, H.,Egelman, E.H. (deposition date: 2013-12-05, release date: 2014-03-26, Last modification date: 2024-02-21) |
Primary citation | Lu, A.,Magupalli, V.G.,Ruan, J.,Yin, Q.,Atianand, M.K.,Vos, M.R.,Schroder, G.F.,Fitzgerald, K.A.,Wu, H.,Egelman, E.H. Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes. Cell(Cambridge,Mass.), 156:1193-1206, 2014 Cited by PubMed: 24630722DOI: 10.1016/j.cell.2014.02.008 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
Download full validation report