3J3Z

Structure of MA28-7 neutralizing antibody Fab fragment from electron cryo-microscopy of enterovirus 71 complexed with a Fab fragment

Summary for 3J3Z

• Entry DOI: 10.2210/pdb3j3z/pdb
• EMDB information: 5673
• Descriptor: MA28-7 neutralizing antibody light chain, MA28-7 neutralizing antibody heavy chain (2 entities in total)
• Functional Keywords: ev71, enterovirus, hfmd, strain-specific eptitope, vp1-145, immune system
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 2
• Total formula weight: 46610.88

Authors

Lee, H.,Cifuente, J.O.,Ashley, R.E.,Conway, J.F.,Makhov, A.M.,Tano, Y.,Shimizu, H.,Nishimura, Y.,Hafenstein, S. (deposition date: 2013-05-21, release date: 2013-08-28, Last modification date: 2018-07-18)

• Primary citation: Lee, H.,Cifuente, J.O.,Ashley, R.E.,Conway, J.F.,Makhov, A.M.,Tano, Y.,Shimizu, H.,Nishimura, Y.,Hafenstein, S.; A strain-specific epitope of enterovirus 71 identified by cryo-electron microscopy of the complex with fab from neutralizing antibody.; J.Virol., 87:11363-11370, 2013; PubMed: 23946455; DOI: 10.1128/JVI.01926-13

Experimental method

ELECTRON MICROSCOPY (23.4 Å)