West Nile virus in complex with Fab fragments of MAb CR4354 (fitted coordinates of envelope proteins and Fab fragments of one icosahedral ASU)

Summary for 3IYW

Related3N9G 2HG0
EMDB information5190
DescriptorPolyprotein, CR4354 Fab fragment X1, heavy chain H, CR4354 Fab fragment X1, light chain L, ... (5 entities in total)
Functional Keywordsvirus-antibody complex, neutralizing fab fragment, flavivirus, west nile virus, envelope protein, icosahedral virus, virus
Biological sourceWest Nile virus (WNV)
Total number of polymer chains7
Total molecular weight228601.31
Rossmann, M.G.,Kaufmann, B. (deposition date: 2010-06-18, release date: 2010-11-24, Last modification date: 2018-07-18)
Primary citation
Kaufmann, B.,Vogt, M.R.,Goudsmit, J.,Holdaway, H.A.,Aksyuk, A.A.,Chipman, P.R.,Kuhn, R.J.,Diamond, M.S.,Rossmann, M.G.
Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354.
Proc.Natl.Acad.Sci.USA, 107:18950-18955, 2010
PubMed: 20956322 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1011036107
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers482.6%2.5%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation report