3IYW
West Nile virus in complex with Fab fragments of MAb CR4354 (fitted coordinates of envelope proteins and Fab fragments of one icosahedral ASU)
Summary for 3IYW
| Entry DOI | 10.2210/pdb3iyw/pdb |
| Related | 2HG0 3N9G |
| EMDB information | 5190 |
| Descriptor | Envelope glycoprotein, CR4354 Fab fragment X1, heavy chain H, CR4354 Fab fragment X1, light chain L, ... (4 entities in total) |
| Functional Keywords | virus-antibody complex, neutralizing fab fragment, flavivirus, west nile virus, envelope protein, icosahedral virus, virus |
| Biological source | West Nile virus More |
| Total number of polymer chains | 7 |
| Total formula weight | 226835.64 |
| Authors | Rossmann, M.G.,Kaufmann, B. (deposition date: 2010-06-18, release date: 2010-11-24, Last modification date: 2024-03-27) |
| Primary citation | Kaufmann, B.,Vogt, M.R.,Goudsmit, J.,Holdaway, H.A.,Aksyuk, A.A.,Chipman, P.R.,Kuhn, R.J.,Diamond, M.S.,Rossmann, M.G. Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354. Proc.Natl.Acad.Sci.USA, 107:18950-18955, 2010 Cited by PubMed: 20956322DOI: 10.1073/pnas.1011036107 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (13.7 Å) |
Structure validation
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