3IU5

Crystal structure of the first bromodomain of human poly-bromodomain containing protein 1 (PB1)

3IU5 の概要

• エントリーDOI: 10.2210/pdb3iu5/pdb
• 分子名称: Protein polybromo-1 (2 entities in total)
• 機能のキーワード: pb1, polybromo 1 isoform 1, baf180, polybromo0id, pbrm1, brg1-associated factor 180, structural genomics, sgc, structural genomics consortium, bromodomain, chromatin regulator, dna-binding, nucleus, phosphoprotein, transcription, transcription regulation
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: Q86U86
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 13896.83

構造登録者

Filippakopoulos, P.,Picaud, S.,Keates, T.,Ugochukwu, E.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2009-08-30, 公開日: 2009-09-22, 最終更新日: 2023-09-06)

• 主引用文献: Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S.; Histone recognition and large-scale structural analysis of the human bromodomain family.; Cell(Cambridge,Mass.), 149:214-231, 2012; PubMed: 22464331; DOI: 10.1016/j.cell.2012.02.013

実験手法

X-RAY DIFFRACTION (1.63 Å)