3ISB

Binary complex of human DNA polymerase beta with a gapped DNA

3ISB の概要

• エントリーDOI: 10.2210/pdb3isb/pdb
• 関連するPDBエントリー: 1BPX 3ISC 3ISD
• 分子名称: DNA polymerase beta, 5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3', ... (7 entities in total)
• 機能のキーワード: nucleotidyl transferase, dna polymerase beta, binary complex, gapped dna, dna damage, dna repair, dna replication, dna synthesis, dna-binding, dna-directed dna polymerase, lyase, magnesium, metal-binding, methylation, nucleotidyltransferase, nucleus, polymorphism, sodium, transferase, transferase-dna complex, transferase/dna
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus: P06746
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 47895.89

構造登録者

Beard, W.A.,Shock, D.D.,Batra, V.K.,Pedersen, L.C.,Wilson, S.H. (登録日: 2009-08-25, 公開日: 2009-09-15, 最終更新日: 2023-09-06)

• 主引用文献: Beard, W.A.,Shock, D.D.,Batra, V.K.,Pedersen, L.C.,Wilson, S.H.; DNA polymerase beta substrate specificity: side chain modulation of the "A-rule".; J.Biol.Chem., 284:31680-31689, 2009; PubMed: 19759017; DOI: 10.1074/jbc.M109.029843

実験手法

X-RAY DIFFRACTION (2 Å)