3IQS
Crystal structure of the anti-viral APOBEC3G catalytic domain
Summary for 3IQS
Entry DOI | 10.2210/pdb3iqs/pdb |
Related | 3E1U |
Descriptor | DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION (3 entities in total) |
Functional Keywords | five beta-strands surrounded by six alpha-helices, alternative splicing, antiviral defense, cytoplasm, host-virus interaction, hydrolase, metal-binding, nucleus, polymorphism, ubl conjugation, zinc |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q9HC16 |
Total number of polymer chains | 1 |
Total formula weight | 22153.40 |
Authors | Holden, L.G.,Prochnow, C.,Chang, Y.P.,Bransteitter, R.,Chelico, L.,Sen, U.,Stevens, R.C.,Goodman, R.F.,Chen, X.S. (deposition date: 2009-08-20, release date: 2009-11-10, Last modification date: 2024-02-21) |
Primary citation | Holden, L.G.,Prochnow, C.,Chang, Y.P.,Bransteitter, R.,Chelico, L.,Sen, U.,Stevens, R.C.,Goodman, M.F.,Chen, X.S. Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications. Nature, 456:121-124, 2008 Cited by PubMed: 18849968DOI: 10.1038/nature07357 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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