3IEX
Schistosoma Purine nucleoside phosphorylase in complex with guanosine
Summary for 3IEX
| Entry DOI | 10.2210/pdb3iex/pdb |
| Related | 1TCV 1TD1 |
| Descriptor | Purine-nucleoside phosphorylase, GUANOSINE, SULFATE ION, ... (6 entities in total) |
| Functional Keywords | purine nucleoside phosphorylase, glycosyltransferase, transferase |
| Biological source | Schistosoma mansoni (Blood fluke) |
| Total number of polymer chains | 3 |
| Total formula weight | 94721.95 |
| Authors | Castilho, M.S.,Pereira, H.M.,Oliva, G.,Andricopulo, A.D. (deposition date: 2009-07-23, release date: 2010-03-16, Last modification date: 2023-11-01) |
| Primary citation | Castilho, M.S.,Postigo, M.P.,Pereira, H.M.,Oliva, G.,Andricopulo, A.D. Structural basis for selective inhibition of purine nucleoside phosphorylase from Schistosoma mansoni: kinetic and structural studies Bioorg.Med.Chem., 18:1421-1427, 2010 Cited by PubMed: 20129792DOI: 10.1016/j.bmc.2010.01.022 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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