3IAL

Giardia lamblia Prolyl-tRNA synthetase in complex with prolyl-adenylate

Summary for 3IAL

Entry DOI	10.2210/pdb3ial/pdb
Descriptor	Prolyl-tRNA synthetase, 5'-O-[(R)-hydroxy{[(2S)-pyrrolidin-2-ylcarbonyl]oxy}phosphoryl]adenosine, GLYCEROL, ... (4 entities in total)
Functional Keywords	aminoacyl-trna synthetase, trna ligase, aars, prors, cysrs, pro(cys)rs, translation, atp-binding, nucleotide-binding, structural genomics, medical structural genomics of pathogenic protazoa, msgpp, ligase, medical structural genomics of pathogenic protozoa
Biological source	Giardia lamblia ATCC 50803
Total number of polymer chains	2
Total formula weight	118461.22
Authors	Larson, E.T.,Merritt, E.A.,Medical Structural Genomics of Pathogenic Protozoa,Medical Structural Genomics of Pathogenic Protozoa (MSGPP) (deposition date: 2009-07-14, release date: 2009-08-11, Last modification date: 2023-09-06)
Primary citation	Larson, E.T.,Kim, J.E.,Napuli, A.J.,Verlinde, C.L.,Fan, E.,Zucker, F.H.,Van Voorhis, W.C.,Buckner, F.S.,Hol, W.G.,Merritt, E.A. Structure of the prolyl-tRNA synthetase from the eukaryotic pathogen Giardia lamblia. Acta Crystallogr.,Sect.D, 68:1194-1200, 2012 Cited by PubMed: 22948920 DOI: 10.1107/S0907444912024699 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation