3I7B
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with bumped kinase inhibitor NM-PP1
Summary for 3I7B
Entry DOI | 10.2210/pdb3i7b/pdb |
Related | 3I79 3I7C 3MWU 3N51 3NCG |
Descriptor | Calmodulin-domain protein kinase 1, 1-(1-methylethyl)-3-(naphthalen-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | protein kinase, calmodulin, ef hand, bumped kinase inhibitor, atp-binding, kinase, nucleotide-binding, serine/threonine-protein kinase, structural genomics, medical structural genomics of pathogenic protozoa, msgpp, transferase |
Biological source | Toxoplasma gondii |
Total number of polymer chains | 1 |
Total formula weight | 55808.64 |
Authors | Larson, E.T.,Merritt, E.A.,Medical Structural Genomics of Pathogenic Protozoa (MSGPP) (deposition date: 2009-07-08, release date: 2010-02-09, Last modification date: 2023-09-06) |
Primary citation | Ojo, K.K.,Larson, E.T.,Keyloun, K.R.,Castaneda, L.J.,Derocher, A.E.,Inampudi, K.K.,Kim, J.E.,Arakaki, T.L.,Murphy, R.C.,Zhang, L.,Napuli, A.J.,Maly, D.J.,Verlinde, C.L.,Buckner, F.S.,Parsons, M.,Hol, W.G.,Merritt, E.A.,Van Voorhis, W.C. Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors. Nat.Struct.Mol.Biol., 17:602-607, 2010 Cited by PubMed: 20436472DOI: 10.1038/nsmb.1818 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.988 Å) |
Structure validation
Download full validation report