3I2X
Crystal structure of a chimeric trypsin inhibitor having reactive site loop of ETI on the scaffold of WCI
Summary for 3I2X
| Entry DOI | 10.2210/pdb3i2x/pdb |
| Related | 1XG6 3I2A |
| Descriptor | Chymotrypsin inhibitor 3 (2 entities in total) |
| Functional Keywords | eti(l)-wci(s), mutant, trypsin inhibitor, chimeric protein, serine protease inhibitor, hydrolase/hydrolase inhibitor, disulfide bond, protease inhibitor, hydrolase inhibitor |
| Biological source | Psophocarpus tetragonolobus (Goa bean) |
| Total number of polymer chains | 2 |
| Total formula weight | 41354.65 |
| Authors | Sen, U.,Khamrui, S.,Dasgupta, J.,Dattagupta, J.K.,Majumder, S. (deposition date: 2009-06-30, release date: 2010-02-02, Last modification date: 2023-11-01) |
| Primary citation | Khamrui, S.,Majumder, S.,Dasgupta, J.,Dattagupta, J.K.,Sen, U. Identification of a novel set of scaffolding residues that are instrumental for the inhibitory property of Kunitz (STI) inhibitors. Protein Sci., 19:593-602, 2010 Cited by PubMed: 20073082DOI: 10.1002/pro.338 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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