3I2X

Crystal structure of a chimeric trypsin inhibitor having reactive site loop of ETI on the scaffold of WCI

3I2X の概要

• エントリーDOI: 10.2210/pdb3i2x/pdb
• 関連するPDBエントリー: 1XG6 3I2A
• 分子名称: Chymotrypsin inhibitor 3 (2 entities in total)
• 機能のキーワード: eti(l)-wci(s), mutant, trypsin inhibitor, chimeric protein, serine protease inhibitor, hydrolase/hydrolase inhibitor, disulfide bond, protease inhibitor, hydrolase inhibitor
• 由来する生物種: Psophocarpus tetragonolobus (Goa bean)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 41354.65

構造登録者

Sen, U.,Khamrui, S.,Dasgupta, J.,Dattagupta, J.K.,Majumder, S. (登録日: 2009-06-30, 公開日: 2010-02-02, 最終更新日: 2023-11-01)

• 主引用文献: Khamrui, S.,Majumder, S.,Dasgupta, J.,Dattagupta, J.K.,Sen, U.; Identification of a novel set of scaffolding residues that are instrumental for the inhibitory property of Kunitz (STI) inhibitors.; Protein Sci., 19:593-602, 2010; PubMed: 20073082; DOI: 10.1002/pro.338

実験手法

X-RAY DIFFRACTION (2.85 Å)