3I0O

Crystal Structure of Spectinomycin Phosphotransferase, APH(9)-Ia, in complex with ADP and Spectinomcyin

3I0O の概要

• エントリーDOI: 10.2210/pdb3i0o/pdb
• 分子名称: Spectinomycin phosphotransferase, ADENOSINE-5'-DIPHOSPHATE, SPECTINOMYCIN, ... (6 entities in total)
• 機能のキーワード: protein kinase, aminoglycoside phosphotransferase, antibiotic resistance, transferase
• 由来する生物種: Legionella pneumophila serogroup 1
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 40505.38

構造登録者

Fong, D.H.,Lemke, C.T.,Hwang, J.,Xiong, B.,Berghuis, A.M. (登録日: 2009-06-25, 公開日: 2010-01-19, 最終更新日: 2024-04-03)

• 主引用文献: Fong, D.H.,Lemke, C.T.,Hwang, J.,Xiong, B.,Berghuis, A.M.; Structure of the antibiotic resistance factor spectinomycin phosphotransferase from Legionella pneumophila.; J.Biol.Chem., 285:9545-9555, 2010; PubMed: 20089863; DOI: 10.1074/jbc.M109.038364

実験手法

X-RAY DIFFRACTION (2.4 Å)