3HVP

CONSERVED FOLDING IN RETROVIRAL PROTEASES. CRYSTAL STRUCTURE OF A SYNTHETIC HIV-1 PROTEASE

Summary for 3HVP

Entry DOI	10.2210/pdb3hvp/pdb
Descriptor	UNLIGANDED HIV-1 PROTEASE (1 entity in total)
Functional Keywords	hydrolase(acid proteinase)
Biological source	Human immunodeficiency virus 1
Cellular location	Gag-Pol polyprotein: Host cell membrane; Lipid-anchor. Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P03369
Total number of polymer chains	1
Total formula weight	10764.64
Authors	Wlodawer, A.,Jaskolski, M.,Miller, M. (deposition date: 1989-08-08, release date: 1989-10-15, Last modification date: 2017-11-29)
Primary citation	Wlodawer, A.,Miller, M.,Jaskolski, M.,Sathyanarayana, B.K.,Baldwin, E.,Weber, I.T.,Selk, L.M.,Clawson, L.,Schneider, J.,Kent, S.B. Conserved folding in retroviral proteases: crystal structure of a synthetic HIV-1 protease. Science, 245:616-621, 1989 Cited by PubMed: 2548279 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation