3HVF

X-ray crystallographic structure of CTX-M-9 S70G in complex with hydrolyzed benzylpenicillin

Summary for 3HVF

• Entry DOI: 10.2210/pdb3hvf/pdb
• Related: 3HLW 3HRE 3HUO
• Descriptor: CTX-M-9 extended-spectrum beta-lactamase, (2R,4S)-2-{(R)-carboxy[(phenylacetyl)amino]methyl}-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid (3 entities in total)
• Functional Keywords: beta-lactamase, blse, ctx-m-9, b-lactam, penicillin, benzylpenicillin, hydrolase
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 56589.74

Authors

Delmas, J.,Leyssene, D.,Dubois, D.,Vazeille, E.,Robin, F.,Bonnet, R. (deposition date: 2009-06-16, release date: 2010-05-26, Last modification date: 2024-05-29)

• Primary citation: Delmas, J.,Leyssene, D.,Dubois, D.,Birck, C.,Vazeille, E.,Robin, F.,Bonnet, R.; Structural insights into substrate recognition and product expulsion in CTX-M enzymes.; J.Mol.Biol., 400:108-120, 2010; PubMed: 20452359; DOI: 10.1016/j.jmb.2010.04.062

Experimental method

X-RAY DIFFRACTION (1.5 Å)