3HRO
Crystal structure of a C-terminal coiled coil domain of Transient receptor potential (TRP) channel subfamily P member 2 (TRPP2, polycystic kidney disease 2)
3HRO の概要
エントリーDOI | 10.2210/pdb3hro/pdb |
関連するPDBエントリー | 3HRN |
分子名称 | Transient receptor potential (TRP) channel subfamily P member 2 (TRPP2), also called Polycystin-2 or polycystic kidney disease 2(PKD2) (2 entities in total) |
機能のキーワード | coiled coil, helix bundle, trimer, calcium, disease mutation, glycoprotein, ion transport, ionic channel, membrane, phosphoprotein, polymorphism, transmembrane, transport, transport protein |
由来する生物種 | Homo sapiens (human) |
細胞内の位置 | Cell projection, cilium membrane ; Multi-pass membrane protein : Q13563 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 5052.89 |
構造登録者 | Yu, Y.,Ulbrich, M.H.,Li, M.-H.,Buraei, Z.,Chen, X.-Z.,Ong, A.C.M.,Tong, L.,Isacoff, E.Y.,Yang, J. (登録日: 2009-06-09, 公開日: 2009-07-28, 最終更新日: 2023-09-06) |
主引用文献 | Yu, Y.,Ulbrich, M.H.,Li, M.H.,Buraei, Z.,Chen, X.Z.,Ong, A.C.,Tong, L.,Isacoff, E.Y.,Yang, J. Structural and molecular basis of the assembly of the TRPP2/PKD1 complex. Proc.Natl.Acad.Sci.USA, 106:11558-11563, 2009 Cited by PubMed: 19556541DOI: 10.1073/pnas.0903684106 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.9 Å) |
構造検証レポート
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