3HR5
M1prime peptide from IgE bound by humanized antibody 47H4 Fab
Summary for 3HR5
Entry DOI | 10.2210/pdb3hr5/pdb |
Descriptor | Fab h47H4 light chain, Fab h47H4 heavy chain, M1prime-derived peptide, ... (5 entities in total) |
Functional Keywords | fab-peptide complex, immune system |
Biological source | Mus musculus More |
Total number of polymer chains | 12 |
Total formula weight | 208103.77 |
Authors | Eigenbrot, C.W.,Ultsch, M.H. (deposition date: 2009-06-08, release date: 2010-05-19, Last modification date: 2011-07-13) |
Primary citation | Brightbill, H.D.,Jeet, S.,Lin, Z.,Yan, D.,Zhou, M.,Tan, M.,Nguyen, A.,Yeh, S.,Delarosa, D.,Leong, S.R.,Wong, T.,Chen, Y.,Ultsch, M.,Luis, E.,Ramani, S.R.,Jackman, J.,Gonzalez, L.,Dennis, M.S.,Chuntharapai, A.,DeForge, L.,Meng, Y.G.,Xu, M.,Eigenbrot, C.,Lee, W.P.,Refino, C.J.,Balazs, M.,Wu, L.C. Antibodies specific for a segment of human membrane IgE deplete IgE-producing B cells in humanized mice. J.Clin.Invest., 120:2218-2229, 2010 Cited by PubMed: 20458139DOI: 10.1172/JCI40141 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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