3HO2

Structure of E.coli FabF(C163A) in complex with Platencin

Summary for 3HO2

Entry DOI	10.2210/pdb3ho2/pdb
Related	3HNZ 3HO9
Descriptor	3-oxoacyl-[acyl-carrier-protein] synthase 2, 2,4-dihydroxy-3-({3-[(2S,4aS,8S,8aR)-8-methyl-3-methylidene-7-oxo-1,3,4,7,8,8a-hexahydro-2H-2,4a-ethanonaphthalen-8-yl]propanoyl}amino)benzoic acid (3 entities in total)
Functional Keywords	fabf, platensimycin, platencin, ketoacyl synthase, acyltransferase, fatty acid biosynthesis, lipid synthesis, transferase
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	45030.71
Authors	Soisson, S.M.,Parthasarathy, G. (deposition date: 2009-06-01, release date: 2010-02-09, Last modification date: 2023-09-06)
Primary citation	Singh, S.B.,Ondeyka, J.G.,Herath, K.B.,Zhang, C.,Jayasuriya, H.,Zink, D.L.,Parthasarathy, G.,Becker, J.W.,Wang, J.,Soisson, S.M. Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis. Bioorg.Med.Chem.Lett., 19:4756-4759, 2009 Cited by PubMed: 19581087 DOI: 10.1016/j.bmcl.2009.06.061 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation