3HLV
Crystal structure of human Estrogen Receptor Alpha Ligand-Binding Domain in complex with a Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide and 16-alpha-hydroxy-estrone ((8S,9R,13S,14R,16R)-3,16-dihydroxy-13-methyl-7,8,9,11,12,14,15, 16-octahydro-6H-cyclopenta[a]phenanthren-17-one
3HLV の概要
エントリーDOI | 10.2210/pdb3hlv/pdb |
分子名称 | Estrogen receptor, Nuclear receptor coactivator 2, (9beta,13alpha,16beta)-3,16-dihydroxyestra-1,3,5(10)-trien-17-one, ... (4 entities in total) |
機能のキーワード | estrogen receptor, lbd, grip peptide, hydroxy-estrone, alternative splicing, dna-binding, glycoprotein, lipid-binding, metal-binding, nucleus, phosphoprotein, polymorphism, receptor, steroid-binding, transcription, transcription regulation, zinc, zinc-finger, activator, hormone, nuclear receptor |
由来する生物種 | Homo sapiens (human) |
細胞内の位置 | Isoform 1: Nucleus. Isoform 3: Nucleus: P03372 Nucleus: Q9WUI9 |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 61618.79 |
構造登録者 | Rajan, S.S.,Kim, Y.,Vanek, K.,Joachimiak, A.,Greene, G.L. (登録日: 2009-05-28, 公開日: 2010-06-02, 最終更新日: 2023-09-06) |
主引用文献 | Rajan, S.S.,Kim, Y.,Vanek, K.,Joachimiak, A.,Greene, G.L. Crystal structure of human alphaER-LBD in complex with GRIP peptide and 16alpha-hydroxyestrone To be Published, |
実験手法 | X-RAY DIFFRACTION (3 Å) |
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