3HKA

Crystal structure of uronate isomerase from Bacillus halodurans complexed with zinc and D-Fructuronate

Summary for 3HKA

• Entry DOI: 10.2210/pdb3hka/pdb
• Related: 2Q08 2Q6E 3HK5 3HK7 3HK8 3HK9
• Descriptor: Uronate isomerase, D-fructuronic acid, CARBONATE ION, ... (6 entities in total)
• Functional Keywords: uronate isomerase, d-fructuronate, mechanism of the reaction, isomerase
• Biological source: Bacillus halodurans C-125
• Total number of polymer chains: 3
• Total formula weight: 151074.04

Authors

Fedorov, A.A.,Fedorov, E.V.,Nguyen, T.T.,Raushel, F.M.,Almo, S.C. (deposition date: 2009-05-22, release date: 2009-08-25, Last modification date: 2023-09-06)

• Primary citation: Nguyen, T.T.,Fedorov, A.A.,Williams, L.,Fedorov, E.V.,Li, Y.,Xu, C.,Almo, S.C.,Raushel, F.M.; The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily.; Biochemistry, 48:8879-8890, 2009; PubMed: 19678710; DOI: 10.1021/bi901046x

Experimental method

X-RAY DIFFRACTION (1.9 Å)