3HIG

Crystal structure of human diamine oxidase in complex with the inhibitor berenil

3HIG の概要

• エントリーDOI: 10.2210/pdb3hig/pdb
• 関連するPDBエントリー: 3hI7 3hII
• 分子名称: Amiloride-sensitive amine oxidase, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: oxidoreductase, copper amine oxidase, topaquinone, tpq, diamine oxidase, dao, human, berenil, diminazene, glycoprotein, heparin-binding, metal-binding, secreted
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 170578.27

構造登録者

McGrath, A.P.,Guss, J.M. (登録日: 2009-05-19, 公開日: 2009-10-20, 最終更新日: 2023-11-01)

• 主引用文献: McGrath, A.P.,Hilmer, K.M.,Collyer, C.A.,Shepard, E.M.,Elmore, B.O.,Brown, D.E.,Dooley, D.M.,Guss, J.M.; Structure and inhibition of human diamine oxidase; Biochemistry, 48:9810-9822, 2009; PubMed: 19764817; DOI: 10.1021/bi9014192

実験手法

X-RAY DIFFRACTION (2.09 Å)