3HFE

A trimeric form of the Kv7.1 A domain Tail

3HFE の概要

• エントリーDOI: 10.2210/pdb3hfe/pdb
• 関連するPDBエントリー: 3HFC
• 分子名称: Potassium voltage-gated channel subfamily KQT member 1 (2 entities in total)
• 機能のキーワード: trimer, atrial fibrillation, cell membrane, cytoplasmic vesicle, deafness, disease mutation, glycoprotein, ion transport, ionic channel, long qt syndrome, membrane, phosphoprotein, potassium, potassium channel, potassium transport, short qt syndrome, transmembrane, transport, voltage-gated channel, transport protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cell membrane ; Multi- pass membrane protein : P51787
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 10160.39

構造登録者

Xu, Q.,Minor, D.L. (登録日: 2009-05-11, 公開日: 2009-09-01, 最終更新日: 2024-02-21)

• 主引用文献: Xu, Q.,Minor, D.L.; Crystal structure of a trimeric form of the K(V)7.1 (KCNQ1) A-domain tail coiled-coil reveals structural plasticity and context dependent changes in a putative coiled-coil trimerization motif.; Protein Sci., 18:2100-2114, 2009; PubMed: 19693805; DOI: 10.1002/pro.224

実験手法

X-RAY DIFFRACTION (1.7 Å)