3HC4

BHA10 IgG1 Fab quadruple mutant variant - antibody directed at human LTBR

Summary for 3HC4

• Entry DOI: 10.2210/pdb3hc4/pdb
• Related: 3HC0
• Descriptor: IMMUNOGLOBULIN IGG1 FAB, HEAVY CHAIN, IMMUNOGLOBULIN IGG1 FAB, LIGHT CHAIN, ACETATE ION, ... (5 entities in total)
• Functional Keywords: igg1 fab, bha10, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 46566.41

Authors

Arndt, J.W.,Jordan, J.L.,Lugovskoy, A.,Wang, D. (deposition date: 2009-05-05, release date: 2009-08-04, Last modification date: 2023-09-06)

• Primary citation: Jordan, J.L.,Arndt, J.W.,Hanf, K.,Li, G.,Hall, J.,Demarest, S.,Huang, F.,Wu, X.,Miller, B.,Glaser, S.,Fernandez, E.J.,Wang, D.,Lugovskoy, A.; Structural understanding of stabilization patterns in engineered bispecific Ig-like antibody molecules; Proteins, 77:832-841, 2009; PubMed: 19626705; DOI: 10.1002/prot.22502

Experimental method

X-RAY DIFFRACTION (1.62 Å)