3H6O
Activator-Bound Structure of Human Pyruvate Kinase M2
Summary for 3H6O
Entry DOI | 10.2210/pdb3h6o/pdb |
Descriptor | Pyruvate kinase isozymes M1/M2, 1,6-di-O-phosphono-beta-D-fructofuranose, UNKNOWN ATOM OR ION, ... (5 entities in total) |
Functional Keywords | activator, allosteric enzyme, glycolysis, kinase, magnesium, metal-binding, phosphoprotein, pyruvate, transferase, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 242215.62 |
Authors | Hong, B.,Dimov, S.,Tempel, W.,Auld, D.,Thomas, C.,Boxer, M.,Jianq, J.-K.,Skoumbourdis, A.,Min, S.,Southall, N.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Bochkarev, A.,Inglese, J.,Park, H.,Structural Genomics Consortium (SGC) (deposition date: 2009-04-23, release date: 2009-05-05, Last modification date: 2023-09-06) |
Primary citation | Hong, B.,Dimov, S.,Tempel, W.,Auld, D.,Thomas, C.,Boxer, M.,Jianq, J.-K.,Skoumbourdis, A.,Min, S.,Southall, N.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Bochkarev, A.,Inglese, J.,Park, H. Activator-Bound Structures of Human Pyruvate Kinase M2 to be published, |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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