3H6O

Activator-Bound Structure of Human Pyruvate Kinase M2

3H6O の概要

• エントリーDOI: 10.2210/pdb3h6o/pdb
• 分子名称: Pyruvate kinase isozymes M1/M2, 1,6-di-O-phosphono-beta-D-fructofuranose, UNKNOWN ATOM OR ION, ... (5 entities in total)
• 機能のキーワード: activator, allosteric enzyme, glycolysis, kinase, magnesium, metal-binding, phosphoprotein, pyruvate, transferase, structural genomics, structural genomics consortium, sgc
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 242215.62

構造登録者

Hong, B.,Dimov, S.,Tempel, W.,Auld, D.,Thomas, C.,Boxer, M.,Jianq, J.-K.,Skoumbourdis, A.,Min, S.,Southall, N.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Bochkarev, A.,Inglese, J.,Park, H.,Structural Genomics Consortium (SGC) (登録日: 2009-04-23, 公開日: 2009-05-05, 最終更新日: 2023-09-06)

• 主引用文献: Hong, B.,Dimov, S.,Tempel, W.,Auld, D.,Thomas, C.,Boxer, M.,Jianq, J.-K.,Skoumbourdis, A.,Min, S.,Southall, N.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Bochkarev, A.,Inglese, J.,Park, H.; Activator-Bound Structures of Human Pyruvate Kinase M2; to be published,

実験手法

X-RAY DIFFRACTION (2 Å)