3H4B

Ternary complex of human DNA polymerase iota with template U/T and incoming dATP

3H4B の概要

• エントリーDOI: 10.2210/pdb3h4b/pdb
• 関連するPDBエントリー: 3H40 3H4O
• 分子名称: DNA polymerase iota, 5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(*TP*(BRU)P*GP*GP*GP*TP*CP*CP*T)-3', ... (6 entities in total)
• 機能のキーワード: dna polymerase iota, replication, dna damage, dna repair, dna replication, dna synthesis, dna-binding, dna-directed dna polymerase, magnesium, metal-binding, mutator protein, nucleotidyltransferase, nucleus, schiff base, transferase, replication-dna complex, replication/dna
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: Q9UNA4
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 49446.61

構造登録者

Jain, R.,Nair, D.T.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K. (登録日: 2009-04-18, 公開日: 2009-07-21, 最終更新日: 2023-09-06)

• 主引用文献: Jain, R.,Nair, D.T.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K.; Replication across template T/U by human DNA polymerase-iota.; Structure, 17:974-980, 2009; PubMed: 19604477; DOI: 10.1016/j.str.2009.04.011

実験手法

X-RAY DIFFRACTION (2.85 Å)