3H2Q

Human SOD1 H80R variant, P21 crystal form

Summary for 3H2Q

• Entry DOI: 10.2210/pdb3h2q/pdb
• Related: 3H2P 3H2R
• Descriptor: Superoxide dismutase [Cu-Zn], ZINC ION, SULFATE ION, ... (4 entities in total)
• Functional Keywords: oxidoreductase, human cu, zn superoxide dismutase, antioxidant, metal-binding, copper, zinc, amyotrophic lateral sclerosis, disease mutation, acetylation, cytoplasm, disulfide bond, phosphoprotein, ubl conjugation
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm: P00441
• Total number of polymer chains: 4
• Total formula weight: 64032.32

Authors

Seetharaman, S.V.,Winkler, D.D.,Taylor, A.B.,Cao, X.,Whitson, L.J.,Doucette, P.A.,Valentine, J.S.,Carroll, M.C.,Culotta, V.C.,Hart, P.J. (deposition date: 2009-04-14, release date: 2010-05-05, Last modification date: 2024-11-20)

• Primary citation: Seetharaman, S.V.,Winkler, D.D.,Taylor, A.B.,Cao, X.,Whitson, L.J.,Doucette, P.A.,Valentine, J.S.,Carroll, M.C.,Culotta, V.C.,Hart, P.J.; Structures of Pathogenic SOD1 Mutants H80R and D124V: Disrupted Zinc-binding and Compromised Post-translational Modification by the Copper Chaperone CCS; To be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)