3H2Q

Human SOD1 H80R variant, P21 crystal form

3H2Q の概要

• エントリーDOI: 10.2210/pdb3h2q/pdb
• 関連するPDBエントリー: 3H2P 3H2R
• 分子名称: Superoxide dismutase [Cu-Zn], ZINC ION, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: oxidoreductase, human cu, zn superoxide dismutase, antioxidant, metal-binding, copper, zinc, amyotrophic lateral sclerosis, disease mutation, acetylation, cytoplasm, disulfide bond, phosphoprotein, ubl conjugation
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Cytoplasm: P00441
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 64032.32

構造登録者

Seetharaman, S.V.,Winkler, D.D.,Taylor, A.B.,Cao, X.,Whitson, L.J.,Doucette, P.A.,Valentine, J.S.,Carroll, M.C.,Culotta, V.C.,Hart, P.J. (登録日: 2009-04-14, 公開日: 2010-05-05, 最終更新日: 2024-11-20)

• 主引用文献: Seetharaman, S.V.,Winkler, D.D.,Taylor, A.B.,Cao, X.,Whitson, L.J.,Doucette, P.A.,Valentine, J.S.,Carroll, M.C.,Culotta, V.C.,Hart, P.J.; Structures of Pathogenic SOD1 Mutants H80R and D124V: Disrupted Zinc-binding and Compromised Post-translational Modification by the Copper Chaperone CCS; To be Published,

実験手法

X-RAY DIFFRACTION (1.85 Å)