3H1X
Simultaneous inhibition of anti-coagulation and inflammation: Crystal structure of phospholipase A2 complexed with indomethacin at 1.4 A resolution reveals the presence of the new common ligand binding site
Summary for 3H1X
Entry DOI | 10.2210/pdb3h1x/pdb |
Related | 1FB2 |
Descriptor | Phospholipase A2 VRV-PL-VIIIa, INDOMETHACIN, SULFATE ION, ... (4 entities in total) |
Functional Keywords | pla2, anti-inflammatory, anti-coagulant, indomethacin, hydrolase |
Biological source | Daboia russellii russellii (Indian Russell's viper) |
Cellular location | Secreted: P59071 |
Total number of polymer chains | 1 |
Total formula weight | 14275.74 |
Authors | Singh, N.,Prem Kumar, R.,Sharma, S.,Kaur, P.,Singh, T.P. (deposition date: 2009-04-14, release date: 2009-06-09, Last modification date: 2023-11-01) |
Primary citation | Singh, N.,Kumar, R.P.,Kumar, S.,Sharma, S.,Mir, R.,Kaur, P.,Srinivasan, A.,Singh, T.P. Simultaneous inhibition of anti-coagulation and inflammation: crystal structure of phospholipase A2 complexed with indomethacin at 1.4 A resolution reveals the presence of the new common ligand-binding site J.Mol.Recognit., 22:437-445, 2009 Cited by PubMed: 19462410DOI: 10.1002/jmr.960 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
Download full validation report