3H1X

Simultaneous inhibition of anti-coagulation and inflammation: Crystal structure of phospholipase A2 complexed with indomethacin at 1.4 A resolution reveals the presence of the new common ligand binding site

3H1X の概要

• エントリーDOI: 10.2210/pdb3h1x/pdb
• 関連するPDBエントリー: 1FB2
• 分子名称: Phospholipase A2 VRV-PL-VIIIa, INDOMETHACIN, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: pla2, anti-inflammatory, anti-coagulant, indomethacin, hydrolase
• 由来する生物種: Daboia russellii russellii (Indian Russell's viper)
• 細胞内の位置: Secreted: P59071
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14275.74

構造登録者

Singh, N.,Prem Kumar, R.,Sharma, S.,Kaur, P.,Singh, T.P. (登録日: 2009-04-14, 公開日: 2009-06-09, 最終更新日: 2023-11-01)

• 主引用文献: Singh, N.,Kumar, R.P.,Kumar, S.,Sharma, S.,Mir, R.,Kaur, P.,Srinivasan, A.,Singh, T.P.; Simultaneous inhibition of anti-coagulation and inflammation: crystal structure of phospholipase A2 complexed with indomethacin at 1.4 A resolution reveals the presence of the new common ligand-binding site; J.Mol.Recognit., 22:437-445, 2009; PubMed: 19462410; DOI: 10.1002/jmr.960

実験手法

X-RAY DIFFRACTION (1.4 Å)