3GXB

Crystal structure of VWF A2 domain

3GXB の概要

• エントリーDOI: 10.2210/pdb3gxb/pdb
• 分子名称: von Willebrand factor, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: vwa-like fold, blood coagulation, cell adhesion, cleavage on pair of basic residues, disease mutation, disulfide bond, extracellular matrix, glycoprotein, hemostasis, isopeptide bond, secreted, von willebrand disease
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43020.08

構造登録者

Zhou, Y.F.,Springer, T.A. (登録日: 2009-04-02, 公開日: 2009-05-05, 最終更新日: 2023-09-06)

• 主引用文献: Zhang, Q.,Zhou, Y.F.,Zhang, C.Z.,Zhang, X.,Lu, C.,Springer, T.A.; Structural specializations of A2, a force-sensing domain in the ultralarge vascular protein von Willebrand factor.; Proc.Natl.Acad.Sci.USA, 106:9226-9231, 2009; PubMed: 19470641; DOI: 10.1073/pnas.0903679106

実験手法

X-RAY DIFFRACTION (1.9 Å)