3GWW
Leucine transporter LeuT in complex with S-fluoxetine
Summary for 3GWW
Entry DOI | 10.2210/pdb3gww/pdb |
Related | 3GWU 3GWV |
Descriptor | Transporter, SODIUM ION, LEUCINE, ... (5 entities in total) |
Functional Keywords | neurotransmitter, transmembrane transport, integral membrane protein, antidepressant, nss, transport protein, symport, transmembrane, transport |
Biological source | Aquifex aeolicus |
Total number of polymer chains | 1 |
Total formula weight | 58097.32 |
Authors | Zhou, Z.,Zhen, J.,Karpowich, N.K.,Law, C.J.,Reith, M.E.A.,Wang, D.N. (deposition date: 2009-04-01, release date: 2009-05-12, Last modification date: 2023-09-06) |
Primary citation | Zhou, Z.,Zhen, J.,Karpowich, N.K.,Law, C.J.,Reith, M.E.,Wang, D.N. Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures. Nat.Struct.Mol.Biol., 16:652-657, 2009 Cited by PubMed: 19430461DOI: 10.1038/nsmb.1602 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.46 Å) |
Structure validation
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