3GUZ
Structural and substrate-binding studies of pantothenate synthenate (PS)provide insights into homotropic inhibition by pantoate in PS's
3GUZ の概要
エントリーDOI | 10.2210/pdb3guz/pdb |
分子名称 | Pantothenate synthetase, PANTOATE (3 entities in total) |
機能のキーワード | pantothenate biosynthesis, substrate binding, competitive inhibition, rossmann fold, non-canonical pantoate binding-site, atp-binding, cytoplasm, ligase, nucleotide-binding |
由来する生物種 | Escherichia coli |
細胞内の位置 | Cytoplasm (Potential): P31663 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 40159.81 |
構造登録者 | Chakrabarti, K.S.,Thakur, K.G.,Gopal, B.,Sarma, S.P. (登録日: 2009-03-30, 公開日: 2010-02-09, 最終更新日: 2024-05-29) |
主引用文献 | Chakrabarti, K.S.,Thakur, K.G.,Gopal, B.,Sarma, S.P. X-ray crystallographic and NMR studies of pantothenate synthetase provide insights into the mechanism of homotropic inhibition by pantoate Febs J., 277:697-712, 2010 Cited by PubMed: 20059543DOI: 10.1111/j.1742-4658.2009.07515.x 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.67 Å) |
構造検証レポート
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