3GUZ

Structural and substrate-binding studies of pantothenate synthenate (PS)provide insights into homotropic inhibition by pantoate in PS's

3GUZ の概要

• エントリーDOI: 10.2210/pdb3guz/pdb
• 分子名称: Pantothenate synthetase, PANTOATE (3 entities in total)
• 機能のキーワード: pantothenate biosynthesis, substrate binding, competitive inhibition, rossmann fold, non-canonical pantoate binding-site, atp-binding, cytoplasm, ligase, nucleotide-binding
• 由来する生物種: Escherichia coli
• 細胞内の位置: Cytoplasm (Potential): P31663
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 40159.81

構造登録者

Chakrabarti, K.S.,Thakur, K.G.,Gopal, B.,Sarma, S.P. (登録日: 2009-03-30, 公開日: 2010-02-09, 最終更新日: 2021-11-10)

• 主引用文献: Chakrabarti, K.S.,Thakur, K.G.,Gopal, B.,Sarma, S.P.; X-ray crystallographic and NMR studies of pantothenate synthetase provide insights into the mechanism of homotropic inhibition by pantoate; Febs J., 277:697-712, 2010; PubMed: 20059543; DOI: 10.1111/j.1742-4658.2009.07515.x

実験手法

X-RAY DIFFRACTION (1.67 Å)