3GS8

An all-RNA hairpin ribozyme A38N1dA38 variant with a transition-state mimic substrate strand

Summary for 3GS8

• Entry DOI: 10.2210/pdb3gs8/pdb
• Related: 3GS1 3GS5
• Descriptor: RNA (5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*GP*U)-3'), RNA (5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3'), RNA (5'-R(P*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3'), ... (7 entities in total)
• Functional Keywords: hairpin ribozyme, rna ribozyme, n1-deazaadenosine, rna
• Total number of polymer chains: 4
• Total formula weight: 20504.54

Authors

Spitale, R.C.,Volpini, R.,Heller, M.G.,Krucinska, J.,Cristalli, G.,Wedekind, J.E. (deposition date: 2009-03-26, release date: 2009-04-21, Last modification date: 2024-02-21)

• Primary citation: Spitale, R.C.,Volpini, R.,Heller, M.G.,Krucinska, J.,Cristalli, G.,Wedekind, J.E.; Identification of an imino group indispensable for cleavage by a small ribozyme.; J.Am.Chem.Soc., 131:6093-6095, 2009; PubMed: 19354216; DOI: 10.1021/ja900450h

Experimental method

X-RAY DIFFRACTION (2.85 Å)