3GRR

Crystal Structure of the complex between S-Adenosyl Homocysteine and Methanocaldococcus jannaschi Dim1.

3GRR の概要

• エントリーDOI: 10.2210/pdb3grr/pdb
• 関連するPDBエントリー: 1QYR 1ZQ9 2H1R 3FUT 3FUU 3FUV 3FUW 3FUX 3FYC 3FYD 3GRU 3GRV 3GRY
• 分子名称: Dimethyladenosine transferase, S-ADENOSYL-L-HOMOCYSTEINE (3 entities in total)
• 機能のキーワード: dimethyladenosine transferase, rossmann fold, ribosomal assembly s-adenosyl-l-methionine, rrna processing, rna-binding, methyl transferase, methyltransferase, s-adenosyl-l-methionine, transferase
• 由来する生物種: Methanocaldococcus jannaschii (Methanococcus jannaschii)
• 細胞内の位置: Cytoplasm : Q58435
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34261.72

構造登録者

Scarsdale, J.N.,Musayev, F.N.,Rife, J.P. (登録日: 2009-03-26, 公開日: 2010-03-31, 最終更新日: 2023-09-06)

• 主引用文献: O'Farrell, H.C.,Musayev, F.N.,Scarsdale, J.N.,Rife, J.P.; Binding of adenosine-based ligands to the MjDim1 rRNA methyltransferase: implications for reaction mechanism and drug design.; Biochemistry, 49:2697-2704, 2010; PubMed: 20163168; DOI: 10.1021/bi901875x

実験手法

X-RAY DIFFRACTION (1.8 Å)