3GQV
Lovastatin polyketide enoyl reductase (LovC) mutant K54S with bound NADP
Summary for 3GQV
Entry DOI | 10.2210/pdb3gqv/pdb |
Related | 3B6Z 3B70 |
Descriptor | Enoyl reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GLYCEROL, ... (4 entities in total) |
Functional Keywords | medium-chain reductase (mdr superfamily), rossmann fold, nadp-binding, oxidoreductase |
Biological source | Aspergillus terreus |
Total number of polymer chains | 1 |
Total formula weight | 41508.38 |
Authors | Ames, B.D.,Smith, P.T.,Ma, S.M.,Kaake, R.,Wong, E.W.,Wong, S.K.,Xie, X.,Li, J.W.,Vederas, J.C.,Tang, Y.,Tsai, S.-C. (deposition date: 2009-03-24, release date: 2009-04-07, Last modification date: 2023-09-06) |
Primary citation | Ames, B.D.,Smith, P.T.,Ma, S.M.,Kaake, R.,Wong, E.W.,Xie, X.,Li, J.W.,Vederas, J.C.,Tang, Y.,Tsai, S.-C. biosynthesis of Lovastatin: Crystal structure and biochemical studies of LOVC, A trans-acting polyketide enoyl reductase To be Published, |
Experimental method | X-RAY DIFFRACTION (1.74 Å) |
Structure validation
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