3GO1

Crystal structure of anti-HIV-1 Fab 268-D in complex with V3 peptide MN

3GO1 の概要

• エントリーDOI: 10.2210/pdb3go1/pdb
• 分子名称: Fab 268-D, light chain, Fab 268-D, heavy chain, Envelope glycoprotein gp160, ... (5 entities in total)
• 機能のキーワード: hiv, v3 loop, antibody-antigen interactions, aids, apoptosis, cell membrane, cleavage on pair of basic residues, disulfide bond, envelope protein, fusion protein, glycoprotein, host-virus interaction, membrane, transmembrane, viral immunoevasion, virion, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 48192.58

構造登録者

Kong, X.P.,Burke, V.J. (登録日: 2009-03-18, 公開日: 2010-06-23, 最終更新日: 2023-09-06)

• 主引用文献: Jiang, X.,Burke, V.,Totrov, M.,Williams, C.,Cardozo, T.,Gorny, M.K.,Zolla-Pazner, S.,Kong, X.P.; Conserved structural elements in the V3 crown of HIV-1 gp120.; Nat.Struct.Mol.Biol., 17:955-961, 2010; PubMed: 20622876; DOI: 10.1038/nsmb.1861

実験手法

X-RAY DIFFRACTION (1.89 Å)