3GJO

Crystal structure of human EB1 in complex with microtubule Tip localization signal peptide of MACF

3GJO の概要

• エントリーDOI: 10.2210/pdb3gjo/pdb
• 分子名称: Microtubule-associated protein RP/EB family member 1, Dystonin (3 entities in total)
• 機能のキーワード: eb1 structural motif, +tip protein complex, sxip motiff, apc/dynactin binding protein, microtubule actin cross-linking factor, cell cycle, cell division, mitosis, phosphoprotein, actin-binding calcium, structural protein, microtubule, actin-binding
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Cytoplasm, cytoskeleton: Q15691
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 45639.09

構造登録者

Honnappa, S.,Steinmetz, M.O. (登録日: 2009-03-09, 公開日: 2009-08-04, 最終更新日: 2023-11-01)

• 主引用文献: Honnappa, S.,Gouveia, S.M.,Weisbrich, A.,Damberger, F.F.,Bhavesh, N.S.,Jawhari, H.,Grigoriev, I.,van Rijssel, F.J.A.,Buey, R.M.,Lawera, A.,Jelesarov, I.,Winkler, F.K.,Wuthrich, K.,Akhmanova, A.,Steinmetz, M.O.; An EB1-binding motif acts as a microtubule tip localization signal; Cell(Cambridge,Mass.), 138:366-376, 2009; PubMed: 19632184; DOI: 10.1016/j.cell.2009.04.065

実験手法

X-RAY DIFFRACTION (2.5 Å)