3GIV

Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance

3GIV の概要

• エントリーDOI: 10.2210/pdb3giv/pdb
• 関連するPDBエントリー: 2V2W 2V2X
• 分子名称: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, HIV-1 peptide, ... (4 entities in total)
• 機能のキーワード: hiv, mhc, escape, antigen, immune recognition, disulfide bond, glycoprotein, host-virus interaction, immune response, membrane, mhc i, phosphoprotein, transmembrane, disease mutation, glycation, immunoglobulin domain, pyrrolidone carboxylic acid, secreted', immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01892; Secreted: P61769
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 89723.67

構造登録者

Stewart-Jones, G.,Iversen, A.K.N.,Jones, E.Y. (登録日: 2009-03-06, 公開日: 2009-06-30, 最終更新日: 2023-11-01)

• 主引用文献: Tenzer, S.,Wee, E.,Burgevin, A.,Stewart-Jones, G.,Friis, L.,Lamberth, K.,Chang, C.-H.,Harndahl, M.,Weimershaus, M.,Gerstoft, J.,Akkad, N.,Klenerman, P.,Fugger, L.,Jones, E.Y.,McMichael, A.J.,Buus, S.,Schild, H.,van Endert, P.,Iversen, A.K.N.; Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance; Nat.Immunol., 10:636-646, 2009; PubMed: 19412183; DOI: 10.1038/ni.1728

実験手法

X-RAY DIFFRACTION (2 Å)