3GIQ

Crystal structure of N-acyl-D-Glutamate Deacylase from Bordetella Bronchiseptica complexed with zinc and phosphonate inhibitor, a mimic of the reaction tetrahedral intermediate.

3GIQ の概要

• エントリーDOI: 10.2210/pdb3giq/pdb
• 関連するPDBエントリー: 3GIP
• 分子名称: N-acyl-D-glutamate deacylase, N-[(R)-hydroxy(methyl)phosphoryl]-D-glutamic acid, ZINC ION, ... (4 entities in total)
• 機能のキーワード: n-acyl-d-glutamate deacylase, amidohydrolase, reaction intermediate, hydrolase
• 由来する生物種: Bordetella bronchiseptica (Alcaligenes bronchisepticus)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 103067.84

構造登録者

Fedorov, A.A.,Fedorov, E.V.,Cummings, J.,Raushel, F.M.,Almo, S.C. (登録日: 2009-03-05, 公開日: 2009-09-01, 最終更新日: 2023-09-06)

• 主引用文献: Cummings, J.A.,Fedorov, A.A.,Xu, C.,Brown, S.,Fedorov, E.,Babbitt, P.C.,Almo, S.C.,Raushel, F.M.; Annotating enzymes of uncertain function: the deacylation of D-amino acids by members of the amidohydrolase superfamily.; Biochemistry, 48:6469-6481, 2009; PubMed: 19518059; DOI: 10.1021/bi900661b

実験手法

X-RAY DIFFRACTION (1.8 Å)