3GG3

Crystal Structure of the Bromodomain of Human PCAF

3GG3 の概要

• エントリーDOI: 10.2210/pdb3gg3/pdb
• 分子名称: Histone acetyltransferase PCAF, CHLORIDE ION (3 entities in total)
• 機能のキーワード: pcaf, k(lysine) acetyltransferase 2b, kat2b, gcn5, gcn5l, p, p/caf, crebbp-associated factor, p300/cbp-associated factor, sgc, structural genomics consortium, acyltransferase, bromodomain, cell cycle, host-virus interaction, nucleus, phosphoprotein, transcription, transcription regulation, transferase
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Nucleus : Q92831
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28380.19

構造登録者

Filippakopoulos, P.,Keates, T.,Picaud, S.,Rehana, K.,Fedorov, O.,Ugochukwu, E.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2009-02-27, 公開日: 2009-03-17, 最終更新日: 2023-09-06)

• 主引用文献: Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S.; Histone recognition and large-scale structural analysis of the human bromodomain family.; Cell(Cambridge,Mass.), 149:214-231, 2012; PubMed: 22464331; DOI: 10.1016/j.cell.2012.02.013

実験手法

X-RAY DIFFRACTION (2.25 Å)