3G2L

Crystal structure of 1-(beta-D-glucopyranosyl)-4-substituted-1,2,3-triazoles in complex with glycogen phosphorylase

3G2L の概要

• エントリーDOI: 10.2210/pdb3g2l/pdb
• 関連するPDBエントリー: 3G2H 3G2I 3G2J 3G2K 3G2N
• 分子名称: Glycogen phosphorylase, muscle form, 1-beta-D-glucopyranosyl-4-naphthalen-1-yl-1H-1,2,3-triazole (3 entities in total)
• 機能のキーワード: glycogen phosphorylase, amide-1, 2, 3-triazole bioisosterism, acetylation, allosteric enzyme, carbohydrate metabolism, glycogen metabolism, glycosyltransferase, nucleotide-binding, phosphoprotein, pyridoxal phosphate, transferase
• 由来する生物種: Oryctolagus cuniculus (Rabbit)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 97876.68

構造登録者

Chrysina, E.D.,Bokor, E.,Alexacou, K.-M.,Charavgi, M.-D.,Oikonomakos, G.N.,Zographos, S.E.,Leonidas, D.D.,Oikonomakos, N.G.,Somsak, L. (登録日: 2009-01-31, 公開日: 2010-02-16, 最終更新日: 2023-11-22)

• 主引用文献: Chrysina, E.D.,Bokor, E.,Alexacou, K.-M.,Charavgi, M.-D.,Oikonomakos, G.N.,Zographos, S.E.,Leonidas, D.D.,Oikonomakos, N.G.,Somsak, L.; Amide-1,2,3-triazole bioisosterism: the glycogen phosphorylase case; Tetrahedron: Asymmetry, 20:733-740, 2009; DOI: 10.1016/j.tetasy.2009.03.021

実験手法

X-RAY DIFFRACTION (2.3 Å)